Palette™ currently only supports open 1.75 mm PLA and PLA-based materials (including PLA-based electrically-conductive, glow-in-the-dark, carbon fiber-infused, magnetic, woodfills, metalfills, etc.).
Palette+™ expands the list of compatible materials. This include printing PLA with PLA, PLA with water-soluble filament (Scaffold from E3D), PETG with PETG, and PLA with flexible TPU. You can learn more about Palette+'s material compatibility in our multi-material guide at http://mm3d.co/multimaterial.